If you're going to drink alcohol in any quantity (is there any other way?) take aspirin or (preferably) ibuprofen instead.
Why? Your body will digest the alcohol first. The tylenol will sit there in your body. It will start to break down but won't be fully metabolized. Some of the products of the "not fully metabolized" tylenol are very toxic to your liver. For that same reason, overdoses of tylenol (or any acetaminophen) are very bad. Even without alcohol.