I have used their r-22 replacement and it is wonderful. I used their leak sealer and refrigerant in my downstairs central AC unit after the AC guy told me he couldn't fix the leak. Ran it for 3 years with no trouble until it locked up (it was over 30 years old). I then inherited a newer unit from a coworker (it's only 20 years old) installed it and ran it on ES-22 all last summer. Works fantastic. It takes less ES-22 than r-22 in the system to get the same level of cooling, therefore it's easier on the compressor and more efficient. It's compatible with all oils, too.
Saved me several hundred dollars.
1986 SE Aero coupe.
3.4 DOHC swap is complete and running, now just have to finish the rest of the car...
[This message has been edited by tesmith66 (edited 01-25-2014).]