What usually breaks them is solid mounts and/or too much torque and sticky tires at launching
the moment of inertia runs a huge shock through the drive train and something usually has to give.
Soft mounts and smaller tires will save the tranny or not hitting hard till you are rolling is also helpful.
the most common place for the MG5 is the case around the area which contains the differential.
the Isuzu has parts inside that go usually before the case does as it was designed to only take
the punishment a low torque motor can give.
My MG5 has probably lasted so long with the 4.3 (since 2000) because,
i use stock type rubber mounts which i replace every 2 years
using 225/50/16 high tread wear tires.
and not HITTING it when i launch... I squeeze the pedal.
I may lose a few 10ths in the quarter... but i spend no time repairing broken parts... and thats a good thing