The sy/ty motor isn't the same as a vortec. The vortec is a different style of intake/injection. It uses a central port injector with six hoses running to poppet valves for each cylinder.
I don't think the vortec was a standard deal until about 94-ish, where as the sy/ty turbo motor was out before that.
The 4.3, as said above, shares the same dimensions for the transmission as a small block. Same clutch, flywheel/flexplate, bolt pattern, etc.
The 4.3 is actually just a 350 with two cylinders lopped off. It's predecessor is a 3.8, which I believe is a similar child of the 305. The 4.3 shares tons of parts with the 350 (rods, pistons, accessories, valvetrain, etc.) so you can get most all of the performance parts you'd ever need for it.
I'd imagine you could use all the existing parts from a v8 swap kit, like Archie's, and just modify/make your own engine mounts. You could use the v8 set as a model, and make your own set just like them with only the position in the cradle adjusted. This would also eliminate and fender-cutting necessary.
The turbo routing could be a bit of a hassle, but if you were willing to re-create all the stuff with custom bends and location of the turbo and such, it'd be quite possible I'd imagine.
Those motors have a ton of stuff you can do to them too. You can check out syty.org to find out more about that. The ECM has been hacked, so custom tuning is possible, and there's tons of performance parts for small blocks and turbos out there 
Just my two cents...
Bryce
88 GT