quote Originally posted by sourmash: We don't have a pandemic. Seems that all injected people are getting Covid19 anyway, so these are garbage injections. How many Smallpox injections does it require to still contract Smallpox?

It doesn't work that way with smallpox.

Smallpox vaccine is administered by puncturing the skin multiple times with a bifurcated needle containing a small quantity of vaccine. A small papule develops after 3 to 5 days, following the virus replication in the dermis. The papule evolves into a vesicular and pustular stage over 8 to 10 days.17 There is typically an indurated area surrounding the central lesion. This is followed by scab formation with development of a residual scar. The process of vesiculation and pustule formation defines a ‘take’ of the vaccine. The take is considered equivocal if a pustule, ulcer, or scab, does not develop at the vaccine site; revaccination is recommended in this situation.17 Skin reactions following revaccination tend to be milder and have an accelerated course.

SNIP

A more safe and effective method for smallpox control originated in the late 18th century when Dr. Edward Jenner of Gloucestershire, England noticed that milkmaids exposed to cowpox appeared to be immune to smallpox. He tested his hypothesis by inoculating a boy with cowpox pus and subsequently challenging him with smallpox. The experiment was a success, and Jenner prepared a paper describing this case along with 13 other individuals who had contracted either horsepox or cowpox before being exposed to smallpox. In one of the worst editorial decisions of all time, the Royal Society rejected the paper and suggested that Jenner cease his cowpox investigations.5 Jenner wisely ignored this advice, named the cowpox material the “vaccine virus”, and thus discovered the concept of vaccination.1, 6 Early smallpox vaccinations utilized pustular material from one vaccinated person to directly inoculate another person by scratching the material into the recipient's arm. Later improvements included the inoculation of cow flanks to obtain larger quantities of virus, and use of glycerol solution as a preservative.

SNIP

ADVERSE EFFECTS OF VACCINATION
Frequency and Clinical Features
Smallpox vaccine is less safe than other vaccines routinely used today. The vaccine is associated with known adverse effects that range from mild to severe. Mild vaccine reactions include formation of satellite lesions, fever, muscle aches, regional lymphadenopathy, fatigue, headache, nausea, rashes, and soreness at the vaccination site.13,18,19 A recent clinical trial reported that more than one-third of vaccine recipients missed days of work or school because of these mild vaccine-related symptoms.18

In the 1960s, serious adverse events associated with smallpox vaccination in the United States included death (1/million vaccinations), progressive vaccinia (1.5/million vaccinations), eczema vaccinatum (39/million vaccinations), postvaccinial encephalitis (12/million vaccinations), and generalized vaccinia (241/million vaccinations).20 Adverse events were approximately ten times more common among those vaccinated for the first time compared to revaccinees.20 Fatality rates were also four times higher for primary vaccinees compared to revaccinees.21

Inadvertent inoculation is the most common adverse event associated with smallpox vaccination. It occurred at a rate of 529 per million vaccinations in a 1968 study.20 Inadvertent or accidental inoculation usually occurs when a person transfers the vaccinia virus from the vaccination site to another location on their body, usually the eyes, mouth, nose, or genitalia.20,22 Most lesions resolve without therapy, but vaccinia immune globulin (VIG) may be useful for difficult lesions. VIG can be considered for use in patients with severe ocular vaccinia, but it may increase the risk of corneal scarring.17,23

Progressive vaccinia (a.k.a. vaccinia necrosum, vaccinia gangrenosum) is defined as an uncontrolled replication of vaccinia virus at the vaccination site that leads to a slow and progressive necrosis of surrounding tissue.24 Satellite necrotic lesions typically develop, and ultimately vaccinia virus may be found in other tissues and organs.24 This condition typically affects individuals with incompetent immune systems.24,25 The cardinal clinical signs of progressive vaccinia include an unhealed vaccination site >15 days post vaccination, and the lack of inflammation or an immune response at the vaccination site.24,25 Untreated progressive vaccinia is fatal, but treatment with VIG or the antiviral cidofovir may be effective in some cases.24,25 VIG and thiosemicarbazone treatment in the late 1960s and 1970s reduced the fatality rate for progressive vaccinia from near 100% to 33%.23,25,26 Surgical debridement or amputation may also provide some benefit.24, 25

Eczema vaccinatum is a cutaneous dissemination of vaccinia virus that usually occurs in persons with pre-existing skin disease. It is typically mild and self-limited, but it may be severe or fatal, especially in young children. Death is usually caused by extensive viral dissemination, fluid and electrolyte imbalance, and bacterial sepsis.25,27 Treatment with VIG or antivirals may be effective in some cases.25 Supportive care used for burn victims may help retain proper fluid and electrolyte balance and reduce mortality from eczema vaccinatum.2 Improvements in intensive care therapy during the 1960s likely contributed to the lowering of the fatality rate for eczema vaccinatum from 10% to 1% to 2%.26,27

Post-vaccinial encephalitis is a rare adverse event that frequently leads to death, especially in infants and young children. Reported case fatality rates range from 9% to 40%.25,28 Ten to twenty-five percent of surviving patients have permanent neurologic sequelae.25,28 No predisposing conditions have been identified for this condition, and treatment with VIG has little to no effect.21,23,25

Generalized vaccinia results from blood-borne dissemination of vaccinia virus.23,25 Patients affected with this condition have a generalized rash that is typically self-limited and requires no therapy. VIG can be administered to speed recovery.23,25 This condition may occur in immunosuppressed individuals, but it can also affect those without any underlying illness or risk factors.25. Hmm Sound familiar?
https://www.ncbi.nlm.nih.go...articles/PMC1069029/

There is a lot of known, accepted and proven research out there if you look.

Rams

[This message has been edited by blackrams (edited 01-03-2022).]

[This message has been edited by sourmash (edited 01-03-2022).]