I have used their r-22 replacement and it is wonderful. I used their leak sealer and refrigerant in my downstairs central AC unit after the AC guy told me he couldn't fix the leak. Ran it for 3 years with no trouble until it locked up (it was over 30 years old). I then inherited a newer unit from a coworker (it's only 20 years old) installed it and ran it on ES-22 all last summer. Works fantastic. It takes less ES-22 than r-22 in the system to get the same level of cooling, therefore it's easier on the compressor and more efficient. It's compatible with all oils, too.
Saved me several hundred dollars.
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1986 SE Aero coupe.
3.4 DOHC swap is complete and running, now just have to finish the rest of the car...
[This message has been edited by tesmith66 (edited 01-25-2014).]