If this is for a V6 the main restriction is the neck in the upper intake manifold . A larger throttle body won't give you much if any more horsepower by just increasing the V6 throttle body bore.
There was a special Holly throttle body made for the Duke but AFAIK it only fits the 87-88 engines. They are hard to come by but we see them for sale ever so often. If you are looking for more Duke power see here:
Iron Duke Resource Site------------------
" THE BLACK PARALYZER" -87GT 3800SC Series III engine, custom ZZP /Frozen Boost Intercooler setup, 3.4" Pulley, Northstar TB, LS1 MAF, 3" Spintech/Hedman Exhaust, P-log Manifold, Autolite 104's, MSD wires, Custom CAI, 4T65eHD w. custom axles, Champion Radiator, S10 Brake Booster, HP Tuners VCM Suite.
"THE COLUSSUS"
87GT - ALL OUT 3.4L Turbocharged engine, Garrett Hybrid Turbo, MSD ign., modified TH125H
" ON THE LOOSE WITHOUT THE JUICE "