Wow, interesting coinsidence.
I just lost both of my CD-ROM drives and my printer two days ago. All were fine and then I restarted and BAM! gone! Everytime I tried reinstalling the drivers it would just say "drivers are corrupted" or some crap like that. Mounted the WinXP CD from my Dad's computer over the network and it still refused to copy from the CD even when I pointed specifically to it... it would just default to my local HD.
After reinstalling WinXP everything is working, and I got a copy of Anitvirus 2002 and everything is okeydokey.
I was thinking it might have been a simple virus I might have picked up off of Morpheus. (Using those download programs is just begging to get hit with one!) I wasn't running any virus software at the time since my "upgrade" to WinXP because SystemWorks 2001 isn't compatible (just like everything else).